Etanercept Market Forecast 2023 - 2031

Report ID : CBI_1357 |  Category : Pharmaceuticals And Healthcare   | Published Date:     |  Format :   ms word  ms Excel  PDF

Segments Covered :
By Drug Type Enbrel, Benepali, and Others
By Form Liquid Solution and Powder for Injections
By Application Juvenile Idiopathic Arthritis, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Others
By Region North America, Europe, Asia Pacific, Latin America, and Middle East & Africa
Report Snapshots :
Base Year: 2022
CAGR: 3.2%
Forecast Year: 2023 - 2031
Revenue 2022: $16,032.50 Mn
Revenue 2023: $16,454.45 Mn
Revenue 2031: $21,184.88 Mn

Etanercept Market Forecast 2023 - 2031

Market Overview :

Consegic Business Intelligence analyzes that the Etanercept market is growing with a CAGR of 3.2% during the forecast period (2023-2031). The market accounted for USD 16,032.50 million in 2022 and USD 16,454.45 million in 2023, and the market is projected to be valued at USD 21,184.88 Million by 2031.

Market Definition :

Etanercept is a biologic medication used to treat a variety of autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, plaque psoriasis, and Crohn's disease. It is a tumor necrosis factor (TNF)-alpha inhibitor, which means that it blocks the activity of TNF-alpha, a protein that plays a key role in inflammation.

Etanercept is administered by injection under the skin (subcutaneously). It is typically given once a week, but the frequency of injections may vary depending on the condition being treated and the patient's response to treatment. Overall, etanercept is a safe and effective medication for many people with autoimmune diseases. It can help to improve quality of life and slow the progression of disease.

Etanercept Market :

Etanercept Market

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Market Dynamics :

Etanercept Market Dynamics

Drivers :

  • Increasing prevalence of autoimmune diseases is driving the market growth.

    Etanercept is a biologic medication that is used to treat a variety of autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, plaque psoriasis, and Crohn's disease. Autoimmune disease is a group of conditions in which the body's immune system attacks healthy tissues and organs. There are over 100 different types of autoimmune diseases, and they can affect any part of the body. Etanercept works by blocking the activity of tumor necrosis factor (TNF)-alpha, a protein that plays a key role in inflammation. Significant growth in autoimmune diseases is driving the market growth. For instance, according to the report by Global Autoimmune Institute in August 2022, Autoimmune diseases are increasing internationally, and the global cases of autoimmune cases are rising by 3–9% a year. In the United States, the number of people with at least one autoimmune disease is closer to 8%. Thus, the growing prevalence of autoimmune disease is driving the demand for etanercept for the treatment of such types of diseases.

  • Growing government initiatives to increase awareness about arthritis.

    Etanercept has a wide range of applications in treating severe autoimmune diseases such as rheumatoid arthritis and psoriatic arthritis. It binds with tumor necrosis factor alpha receptor and is used under the brand name Embrel in the market. With the rising cases of various arthritis across the regions, government authorities initiate awareness campaigns and programs to educate the population about the severities caused by these disorders. For instance, as of 13th June 2023, CDC's Arthritis Management and Wellbeing Program has initiated evidence-based public awareness campaigns to promote physical activity and self-management education as useful approaches to managing arthritis. This campaign aims to promote physical activity to Spanish-speaking Americans with arthritis between the ages of 45–64, with an annual income of USD 35,000 or less. With the growing knowledge and awareness among people about applications of etanercept in arthritis, the market is anticipated to grow at a substantiate rate.

Restraint :

  • Side effects associated with utilization of etanercept.

    Etanercept is a highly effective biologic drug used to treat a variety of autoimmune diseases. However, it is associated with several side effects, some of which can be serious. These side effects can deter patients from taking etanercept or cause them to stop taking it altogether, which can restrain market growth. Etanercept injections decrease the tolerance level of the individual to take more injections and increase the susceptibility to get infected easily by several viral, bacterial, and fungal infections that spread throughout the entire body. Such infections, if not treated properly, may lead to fatalities. Other severe common conditions developed through etanercept injections include problems like headache, nausea, and weakness in the body. Hence, it is firmly advised to take etanercept injections in hospitals to avoid any unfortunate circumstances. Even a little fluctuation in the amount of dosage leads to unwanted side effects and presents a severe threat to the patient. Thus, it is evident that the severe side effects associated with the use of etanercept create valid fright among the users and motivate them to look for other alternatives. Consequently, the market experiences a slowdown in operational activities, and the growth of the market is impeded. As a result, the toxicity of Etanercept to the environment and human health is hampering market growth.

Opportunities :

  • Increasing development of biosimilar etanercept products

    Biosimilars are highly similar versions of biologic drugs that have been approved for marketing. They are typically less expensive than the original biologic drugs, and they are expected to play an increasingly important role in the etanercept market in the forecast years. Biosimilar etanercept products are expected to increase access to etanercept treatment for patients in developed and emerging markets. Furthermore, biosimilars are expected to drive down the cost of etanercept treatment. Increasing launches of new biosimilar etanercept products are expected to drive market growth.

    For instance, in August 2020, Lupin and Mylan launched Nepexto biosimilar etanercept, in the German market. Nepexto is a biosimilar to Enbrel, a leading treatment for autoimmune diseases. Nepexto is approved for all therapeutic indications of Enbrel, including moderate to severe rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, axial spondylarthritis, and plaque psoriasis. The launch of Nepexto in Germany is expected to increase access to affordable and effective treatment for patients with autoimmune diseases. Overall, the increasing development of biosimilar etanercept products is expected to positively drive the global etanercept market over the forecast period.

 

Etanercept Market Report Coverage :

Report Attributes Report Details
Study Timeline 2017-2031
Market Size in 2031 USD 21,184.88 Million
CAGR (2023-2031) 3.2%
By Drug Type Enbrel, Benepali, and Others
By Form Liquid Solution and Powder for Injections
By Application Juvenile Idiopathic Arthritis, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Others
By Region North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa
Key Players Pfizer Limited., Amgen Inc., Samsung Bioepis, Lupin, Novartis, Clover Biopharmaceuticals, and AbbVie Inc.

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Market Segmentation :

By Drug Type :

The drug type of segmentation is categorized into enbrel, benepali, and others. In 2022, benepali accounted for the highest market share in the etanercept market, and it is also expected to hold the highest CAGR over the forecast period. Benepali is a biosimilar version of etanercept. Biosimilars are highly similar versions of biologic drugs that have been approved for marketing. They are typically less expensive than the original biologic drugs, and they are expected to play an increasingly important role in the etanercept market.

Benepali is more affordable than the original etanercept product, Enbrel. This makes it a more attractive option for patients and payers, especially in emerging markets where the cost of healthcare is a major concern. Significant growth in healthcare expenditure is the primary factor driving the demand for benepali across the globe. For instance, according to the report by General Government Expenditure (GGE) in April 2023, the share of health sector spending has steadily increased from 3.94% to 5.02% between 2014-15 and 2019-2020. Thus, the increasing spending on healthcare and the high benefits of benepali over Enbrel is driving the segment growth across the globe over the forecast period.

By Form :

The form segment is categorized into liquid solution and powder for injections. In 2022, the powder for injections segment accounted for the highest market share in the etanercept market. Powder for injection form of etanercept is more convenient to administer than the liquid solution form. It can be self-injected at home, which eliminates the need for frequent visits to the doctor's office. Furthermore, powder for injection form of etanercept is more cost-effective than the liquid solution form. This is because the powder form can be stored at room temperature, while the liquid form needs to be refrigerated. This can save patients and healthcare providers money on storage costs. Thus, the powder-for-injection form of etanercept is a highly used and in-demand drug due to its ease of administration, cost-effectiveness, flexibility, versatility, and the increasing prevalence of autoimmune diseases.

By Application :

The application segment is categorized into juvenile idiopathic arthritis, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and others. In 2022, the rheumatoid arthritis segment accounted for the highest market share of 32.50% in the application segment, and it is also expected to hold the highest CAGR over the forecast period. Etanercept is a highly effective treatment for the treatment of rheumatoid arthritis. It is a biologic drug that works by blocking the activity of tumor necrosis factor (TNF)-alpha, a protein that plays a key role in inflammation. Etanercept can help to reduce inflammation, pain, and swelling in patients with RA, and it can also slow the progression of the disease. The growing prevalence of rheumatoid arthritis is further driving the application growth across the globe. For instance, according to the report by the World Health Organization in June 2023, in 2019, 18 million people worldwide were living with rheumatoid arthritis, 13 million people with rheumatoid arthritis experience severity levels (moderate or severe) that could benefit from rehabilitation. Thus, the growing demand for etanercept for the treatment of rheumatoid arthritis is due to its high efficacy, safety, and convenience thus driving the market growth.

Global Etanercept Market, By Application, 2022

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By Region :

The regional segment includes North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

 
North America Etanercept Market, 2022 (USD Million)

Regional Growth Insights

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In 2022, North America accounted for the highest market share at 38.30% valued at USD 6,140.45 Million in 2022 and USD 6,310.28 Million in 2023, it is expected to reach USD 8,139.23 Million in 2031. In North America, the U.S. accounted for the highest market share of 62.70% in the base year 2022. The high prevalence of autoimmune diseases across the region is driving the market growth across North America. For instance, the National Institutes for Health (NIH) estimates that autoimmune diseases affect between 5% and 8% of the U.S. population. This is the third most common cause of chronic illness in the United States. Thus, the growing prevalence of autoimmune disease in the North America region is driving demand for etanercept, which is used in a variety of autoimmune disease treatments.

Furthermore, the Asia Pacific region is expected to witness significant growth over the forecast period, growing at a CAGR of 3.9% during 2023-2031. The significant growth in the pharmaceutical and healthcare industry as well as the growing geriatric population across the region is increasing demand for etanercept. For instance, according to a report by Asia Development Bank, by 2050, one in four people in Asia and the Pacific will be over 60 years old. The population of older persons (aged over 60) in the region will triple between 2010 and 2050, reaching close to 1.3 billion people. Thus, the significant growth in geriatric is expected to create opportunities for growth in the etanercept market over the forecast period.

North America Etanercept Market, By Countries (2022)

Details Countries Growth Insights

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Etanercept Market Competitive Landscape:

The etanercept market is highly competitive, with several large players and numerous small and medium-sized enterprises. These companies have strong research and development capabilities and a strong presence in the market through their extensive product portfolios and distribution networks. The market is characterized by intense competition, with companies focusing on expanding their product offerings and increasing their market share through mergers, acquisitions, and partnerships. The key players in the market include-

Recent Developments :

  • In March 2022, Pfizer launches ENBREL SmartClic, a new self-injecting device for ENBREL patients in Australia, with a companion smartphone app. ENBREL is a tumor necrosis factor (TNF) inhibitor indicated for the treatment of diseases such as Rheumatoid Arthritis (RA), which affects close to half a million Australians and is expected to increase.
  • In March 2021, Samsung Bioepis Co., Ltd. announced the expansion of its global footprint to Australia with the launch of HADLIMA i (adalimumab), a biosimilar referencing HUMIRA ii(adalimumab) for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult and pediatric Crohn's disease, ulcerative colitis, hidradenitis suppurativa and plaque psoriasis.
 

Frequently Asked Question

What was the market size of the etanercept market in 2022?+

In 2022, the market size of etanercept was USD 16,032.50 million.

What will be the potential market valuation for the etanercept industry by 2031?+

In 2031, the market size of Etanercept will be expected to reach USD 21,184.88 million.

What are the key factors driving the growth of the etanercept market?+

Increasing prevalence of autoimmune diseases across the globe is fueling market growth at the global level.

What is the dominant segment in the etanercept market for the application?+

In 2022, the rheumatoid arthritis segment accounted for the highest market share of 32.50% in the overall etanercept market.

Based on current market trends and future predictions, which geographical region is the dominating region in the etanercept market?+

North America accounted for the highest market share in the overall market.