Closed System Transfer Device Market - Size, Share, Industry Trends, and Forecasts (2025 - 2032)

By Type:

Based on type, the (CSTD) market is segmented into membrane-to-membrane systems and needleless systems.

The membrane-to-membrane systems segment accounted for the largest revenue in the closed system transfer device market share in 2024.

• Membrane-to-membrane systems are extensively used due to their superior capability to prevent hazardous drug leakage and ensure airtight sealing.
• These systems employ dual-membrane barriers that create a secure transfer environment, minimizing contamination risks during drug preparation and administration.
• Membrane-to-membrane systems are particularly suitable for handling cytotoxic drugs used in chemotherapy treatments, ensuring safety for healthcare professionals and patients.
• The increasing prevalence of cancer, which has heightened the demand for chemotherapy drugs, has significantly contributed to the adoption of membrane-to-membrane systems.
• Additionally, the growing focus on workplace safety in healthcare institutions and adherence to stringent regulatory guidelines have further bolstered the demand for these systems globally.

The needleless systems segment is anticipated to register the fastest CAGR during the forecast period.

• Needleless systems are rapidly gaining traction as a safer alternative to traditional systems.
• These systems eliminate the risk of needle-stick injuries, a common hazard for healthcare workers handling hazardous drugs.
• Needleless CSTDs are designed to simplify workflows, reduce handling time, and improve overall safety during drug transfer.
• The rising adoption of needleless technology in oncology clinics, pharmacies, and ambulatory surgical centers is driving segment closed system transfer device market growth.
• Furthermore, the ongoing advancements in needleless designs to enhance compatibility with existing medical equipment are expected to boost their adoption.

By Component:

Based on components, the (CSTD) market is segmented into vial access devices, syringe safety devices, bag/line access devices, and accessories.

The vial access devices segment accounted for the largest revenue in the closed system transfer device market share in 2024.

• Vial access devices are crucial for safely accessing and transferring drugs from vials to syringes or infusion bags.
• These devices form an airtight seal to prevent contamination and protect against hazardous drug exposure.
• Vial access devices are widely used in hospitals and pharmacies, where large volumes of drug compounding and preparation occur.
• The increasing demand for chemotherapy drug preparation and the growing use of hazardous drugs in treating chronic diseases have reinforced the trends for vial access devices in the market.

The syringe safety devices segment is anticipated to register the fastest CAGR during the forecast period.

• Syringe safety devices are designed to ensure the secure handling of hazardous drugs during preparation and administration.
• These devices help prevent spills, leaks, and accidental exposure to toxic substances.
• Their application is expanding across oncology clinics and ambulatory surgical centers, where high volumes of drug administration occur.
• The growing focus on protecting healthcare workers from occupational hazards, combined with advancements in syringe safety technology, is expected to drive significant growth in this segment.

By Technology:

The diaphragm-based systems segment accounted for the largest revenue share in 2024.

• Diaphragm-based systems are widely adopted due to their reliable sealing mechanism, preventing drug aerosolization and contamination.
• These systems use a flexible diaphragm to create a physical barrier, ensuring sterility and safety during drug transfer.
• Their extensive use in chemotherapy drug preparation and hazardous drug handling has made them a critical component in hospital pharmacies and oncology clinics.
• The increasing prevalence of cancer and the rising adoption of diaphragm-based CSTDs in healthcare facilities have strengthened their market position.

The air cleaning/filtration systems segment is anticipated to register the fastest CAGR during the forecast period.

• Air cleaning/filtration systems capture airborne contaminants, providing an additional safety layer during hazardous drug handling.
• These systems are essential in compounding and administration processes, where the prevention of toxic particle release is critical.
• Rising awareness of healthcare worker safety and compliance with regulatory standards are driving their adoption in hospitals and specialized clinics.
• Growing investments in advanced air filtration technologies are further supporting the rapid expansion of this segment.

By Application:

The chemotherapy drug administration segment accounted for the largest revenue of 42.30% share in 2024.

• CSTDs are indispensable for minimizing exposure to toxic substances during chemotherapy drug administration.
• These devices ensure a contamination-free transfer process, protecting both healthcare workers and patients.
• The rising global prevalence of cancer and increasing use of cytotoxic drugs in oncology treatments are driving closed system transfer device market demand for CSTDs in this segment.
• Regulatory mandates requiring the use of CSTDs in chemotherapy drug handling have further solidified this segment’s trends.

The hazardous drug handling segment is anticipated to register the fastest CAGR during the forecast period.

• CSTDs are critical in mitigating exposure risks during hazardous drug compounding, preparation, and administration.
• These devices ensure compliance with occupational safety guidelines and regulatory standards, such as OSHA and NIOSH.
• Growing adoption in pharmacies, oncology clinics, and ambulatory surgical centers highlights their importance in healthcare settings.
• Increasing focus on workplace safety and advancements in drug handling technologies are expected to drive growth in this segment.

By End-Use:

Based on end-use, the (CSTD) market is segmented into hospitals, oncology clinics, ambulatory surgical centers, and others.

The hospitals segment accounted for the largest revenue share in 2024.

• Hospitals are major end-users of CSTDs due to the high volume of chemotherapy treatments and hazardous drug-handling procedures, especially in oncology departments and pharmacies.
• CSTDs are essential for ensuring healthcare worker safety by minimizing exposure to cytotoxic drugs and enhancing compliance with regulatory standards such as OSHA and NIOSH guidelines.
• Rising cancer prevalence and growing investments in oncology care infrastructure have led hospitals to adopt advanced CSTD technologies to meet increasing demand.
• Hospitals also focus on improving operational efficiency, reducing drug wastage, and maintaining sterility, which further drives the adoption of CSTDs across these facilities.

The oncology clinics segment is anticipated to register the fastest CAGR during the forecast period.

• Oncology clinics are rapidly adopting CSTDs to safely handle and administer chemotherapy drugs for outpatient cancer treatments, where safety and efficiency are critical.
• The expansion of oncology clinics globally, driven by rising cancer incidences and the preference for cost-effective outpatient care trends, has increased the use of CSTDs.
• Technological advancements, such as needleless systems and compact CSTD designs, have made these devices more accessible and easier to integrate into clinical workflows.
• Growing awareness of regulatory compliance and the benefits of CSTDs for protecting staff and patients from hazardous drug exposure is accelerating their adoption in oncology clinics.